Tissue-specific molecular heterogeneity of human growth hormone-releasing hormone receptor protein.

Comparison of Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variant 1 in Different Stages of Endometriosis

Purification of Large Quantities of Biologically Active Recombinant Human Growth Hormone

Production and purification of human growth hormone using a simple method was studied in two recombinantEscherichia coli, D7-5 and C27-2 strains. The r-hGH was expressed in the form of inclusion body in a batchfermentation process and purified to 99% purity using a procedure based on acid precipitation of the hostderived proteins and other impurities. The effect of the pH and ...

Neither bovine somatotropin nor growth hormone-releasing factor alters expression of thyroid hormone receptors in liver and mammary tissues.

Physiological effects of thyroid hormones are mediated primarily by binding of triiodothyronine to specific nuclear receptors. Organ-specific changes in production of triiodothyronine from its prohormone, thyroxine, have been hypothesized to target the action of thyroid hormones on the mammary gland and play a role in mediating or augmenting a galactopoietic response to bovine somatotropin (bST...

[Frontiers in Bioscience 9, 8-23, January 1, 2004] 8 AP-1 TARGETS IN THE BRAIN

1. Abstract 2. Introduction 3. AP-1 as a transcription factor 4. Defining AP-1-driven gene expression in the brain: technical considerations 5. Putative AP-1 target genes 5.1. Genes encoding the transmembrane and extracellular proteins 5.1.1. Tissue inhibitor of metalloproteinases-1 (timp-1) 5.1.2. Growth-associated protein 43 (GAP-43, B50, neuromodulin, F1, PP46) 5.1.3. Angiotensin II type 1 r...

Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors.

GH release is thought to occur under the reciprocal regulation of two hypothalamic peptides, GH releasing hormone (GHRH) and somatostatin, via their engagement with specific cell surface receptors on the anterior pituitary somatotroph. In addition, GH-releasing peptides, such as GHRP-6 and the nonpeptide mimetics, L-692,429 and MK-0677, stimulate GH release through their activation of a distinc...